健肺胶囊治疗慢性阻塞性肺疾病稳定期疗效观察

《健肺胶囊治疗慢性阻塞性肺疾病稳定期疗效观察》由会员上传分享，免费在线阅读，更多相关内容在学术论文-天天文库。

1、健肺胶囊治疗慢性阻塞性肺疾病稳定期疗效观察作者：郭文新张凤宇阎国良【摘要】　　目的观察健肺胶囊对慢性阻塞性肺疾病（COPD）稳定期的临床疗效、中医证候积分及6min步行距离的影响。方法将100例COPD稳定期患者随机分为2组，对照组50例予氧疗、身体锻炼、口服茶碱制剂及沐舒坦、吸入长效β2受体激动剂等西医常规基础治疗，治疗组50例在对照组治疗基础上加用自拟健肺胶囊，每次2～3粒，每日3次口服。2组均14日为1个疗程，治疗2个疗程。观察2组治疗前后中医证候积分及6min步行距离，并判定临床疗效。结果①临床疗效：治疗组总有效率96％，对照组总有效率84％，治疗组

2、疗效明显优于对照组（P<0.05）；②中医证候积分：2组治疗后与治疗前比较差异均有统计学意义（P<0.01），且2组治疗后比较差异有统计学意义（P<0.05）；③6min步行距离:2组治疗后均较治疗前改善（P＜0.05），2组治疗后比较差异有统计学意义（P＜0.05）。结论健肺胶囊对COPD稳定期患者的临床疗效、症状、体征及劳动耐力均有明显改善。【关键词】肺疾病阻塞性胶囊剂慢性病补肺随机对照试验中西医结合疗法10　　ClinicalobservationofthetherapeuticeffectofJianfeicapsuleonchro

3、nicobstructivepulmonarydiseaseatstationaryphase　　【Abstract】ObjectiveToobservethetherapeuticeffectofJianfeicapsuleonchronicobstructivepulmonarydiseaseatstationaryphaseaswellastheTCMscoringofsymptomsandtheeffectofindexof6-mindistancewalk.Methods100casedwithchronicobstructivepulmonary

4、diseasewererandomlydividedinto2groupswith50ineach.ThecontrolgroupwastreatedbyroutinemedicaltreatmentlikeoxygentherapyandphysicalexercisewiththeophyllineandMucosolvan,inhalinglong-termβ2receptorstimulatingagent.Thetreatmentgroupwas,onthebasisofcontrolgroup,treatedbyJianfeicapsule,2～

5、3pillseachtime,3timesadayperos.Bothgroupshavethetreatmentcourseof28days(14daysforeverycourse).TheTCMscoringandtheindexof6-minwalkinginbothgroupswereevaluated.Results①TherapeuticEffect:thetotaleffectiverateintreatmentgroupwas96%,whichwas84%incontrolgroup.Theformergroupwasobviouslysu

6、periortothelatterone(P<0.05)②TCMScoring:therewasasignificantdifferencebetweentwogroupsbeforeandafterthetreatment(P<0.01).Therewasa10significantdifferencebetweentwogroupsafterthetreatment(P<0.05)③6-minDistanceWalking:bothgroupswereimprovedcomparedwiththeformerstate(P<0.0

7、5),therewasasignificantdifferencebetweencontrolgroupandtreatmentgroupafterthetreatment(P<0.05).ConclusionJianfeicapsuleiseffectiveintreatingchronicobstructivepulmonarydiseaseatstationaryphase.　　【KeyWords】Pulmonarydisease;Obstructive;Capsule;Chronicdisease;Tonifyingthelung;Random

8、controltest;Integratedther