益气养阴活血通络法联合缬沙坦治疗早期糖尿病肾病临床观察

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1、目录中文摘要······································································································1英文摘要······································································································3英文缩写···············································

2、·······················································5研究论文益气养阴活血通络法联合缬沙坦治疗早期糖尿病肾病前言······································································································6资料与方法··········································································

3、···············7结果······································································································10附表······································································································12讨论·····································

4、·································································16结论······································································································21参考文献··························································································

5、·22综述一糖尿病肾病中西医治疗进展··························································25综述二糖尿病肾病的现代医学研究进展··················································29致谢······································································································36个人简历··········

6、····························································································37益气养阴活血通络法联合缬沙坦治疗早期糖尿病肾病临床观察摘要目的：观察应用益气养阴化瘀通络的中药组方联合缬沙坦，治疗早期糖尿病肾病的疗效。为临床治疗早期糖尿病肾病提供借鉴和参考。方法：收集2016年6月-2017年6月北京燕化医院内分泌门诊的80例早期糖尿病肾病患者。应用随机数字表随机分为二组，两组均予以降糖、降脂、降压等基础治疗，对照组：基础治

7、疗上加用缬沙坦治疗。试验组：基础治疗上应用中药益气养阴活血通络加缬沙坦治疗。所有病例治疗8周，检测治疗前后糖化血红蛋白、尿微量白蛋白定量、血脂、肾功及中医症状评分，以评价中西医结合治疗早期糖尿病肾病的疗效。结果：应用中医证候量表，观察两组的症状积分改变，结果显示：试验组的临床症状的减轻显效率为32.5%，有效率37.5%，总有效率70%，对照组临床症状的减轻显效率5%，有效率37.5%，总有效率42.5%，两组总有效率经卡方检验，P<0.05，差异有统计学意义。两组患者经治疗8周后，结果显示：尿微量白蛋白的减少。试验组显效率为7

8、0%，有效率为20%，总有效率为90%；对照组显效率为32.5%，有效率为35%，总有效率为67.5%，两组总有效率经卡方检验，P<0.05,差异有统计学意义。治疗前后血脂方面，试验组总胆固醇达标率试验组为62.5%，对照组为30%，两组达标率经卡方检验，P<0