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1、-------ABSTRACTBoneHistomorphometricStudyofEffectsofExercisesonWeightedandNonweightBearingBoneMassoftheOrchidectomizedRatsObjectiveThispaperdiscussedtheeffectandmechanismofdifferentintensitytreadmillexerciseonweightedandnonweightbearingbonemassoftheorchid
2、ectomizedRats.MethodsFortymaleSpragueDawlyratsagedat12weeksweredividedintofollowinggroups:SHAM,ORX,threegroupsofindividualexerciseofdifferentintensity:ORX+EX1,ORX+EX2andORX+EX3.Afterrunningfor10weeks,wekillthemandchooseproximaltibiametaphysis(PTM)andthe4t
3、hlumbarvertebralbody(L4)tomakebonesliceswithoutdecalcification,meanwhile,todeterminatediversebonemassindexsandbonearchitectureindexsandbonemetabolismofbonemorphologicalmetrologyandmakeANOVA.Results(1)TheindexsofORXtocompareSHAMshows:bonemassdowns（P<0.05）,
4、bonearchitecturetodestroy（P<0.05）,ossificationtoweaken（P<0.05）,osteoclasttoincrease（P<0.05）.(2)TheindexsofORX+EX1andORX+EX2tocompareORXshows:bonemasstoincreas（eP<0.05）,bonearchitecturetoimprov（eP<0.05）,ossificationtoincreas（eP<0.05）,osteoclasttoweaken（P<0
5、.05）.(3)TheindexsofORX+EX2tocompareORX+EX1shows:bonemasstoincrease（P<0.05）,bonearchitecturetoimprove（P<0.05）,ossificationtoincrease（P<0.05）.(4)TheindexsofORX+EX3tocompareORXshow:bonemassandbonearchitectureisnotdifference（P>0.05）,butossificationandosteocla
6、sttoincrease（P<0.05）,bonemetabolismtoincrease（P<0.05）;theindexsofORX+EX3tocompareORX+EX2show:bonemassdowns（P<0.05）,bonearchitecturetodestroy（P<0.05）,osteoclasttoincrease（P<0.05）.(5)ThebonemassincrementofPTMofORX+EX2ismorethanL4.Conclusion1.theorchidectomi
7、zedRatswilllosebonemassandbone,sarchitecture.2.-----------II万方数据-----------pertinencerunningexercisewillincreasebonemassandbone,sarchitecture.3.runningexcessexercisewillnotmaintainbonemassandbone,sarchitecture.4.Afterpertinencerunningexercisethebonemassin
8、crementofweight-bearingboneismorethannonweight-bearingbone.Subjectwordsrat，orchidectomized，runexercises，bonemass，bone,sarchitecture，weight-bearingbone，nonweight-bearingbone，histomorphometry-----------III万方数据--------
