益气养阴清肝方治疗阴虚阳亢型graves病的临床疗效观察

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1、提要目的:观察益气养阴清肝方在治疗中医辨证属于阴虚阳亢型Graves病的临床疗效，比较中药与西药在消除甲状腺肿大疗效上的差异，以及对患者实验室相关指标的影响，为临床使用提供理论依据。方法:采用随机、对照的方法,将60例阴虚阳亢型Graves病患者随机分为治疗组和对照组，各30例。所有受试者在接受治疗时均进行基础治疗，治疗组在此基础上加用中药益气养阴清肝方进行治疗，对照组在此基础上加用他巴唑进行治疗。观察时间为8周，主要观察指标：临床症状、心率、体重、基础代谢率、甲状腺肿、突眼度、甲功、肝功、血常规等。结果：治疗组治疗后临床症状积分、心率、体重、

2、基础代谢率、甲状腺肿、突眼度、甲功等较前改善明显，与对照组比较有显著性差异。试验期间未发现不良反应。结论：益气养阴清肝方联合行为干预方式对阴虚阳亢型Graves病患者疗效显著，可以明显改善患者临床症状、心率、体重、基础代谢率、甲状腺肿、突眼度、甲功等，且用药安全，证明了中医药辩证论治的有效性，正确运用中医药辨证施治治疗Graves病前景广阔。关键词临床观察；Graves病；阴虚阳亢型；益气养阴清肝方TheClinicalObservationinTreatingQiandYindeficiencysyndromeofGravesDiseasew

3、ithYiQiYangYinQingGanFangSpecialty：InternalMedicineofTraditionalChineseMedicineAuthor：SunXuminTutor：Pro.XuYunshengAbstractObjective：ObservetheclinicalcurativeeffectionofChinesepatentdrug“YiQiYangYinQingGanFang”intreatingQiandYindeficiencysyndromeofGravesDisease,thedifference

4、effectbetweenChinesemedicineandwesternmedicineinremovingThyromegalyiscompared，andthereeffectsinsomelaboratorydataarealsocompared，Offeringatheoreticalbasisfortheclinicaluse.Methods：Takingthemethodofrandomandantitheses，60patientswithQiandYindeficiencysyndromeofGravesDiseasewer

5、edividedintotreatmentgroup（n=30）andthecontrolgroup（n=30）.Alltheparticipantshadreceivedthebasiccure，thetreatmentgroupreceivedthebasiccureplusYiQiYangYinQingGanFang，anothergroupreceivedthebasiccureplustapazole.Observationtimelastfor8weeks，themainoutcomemeasuresareasfollows：the

6、clinicalsymptoms，heartrate，weight，basalmetabolicrate（BMR），thyrocele，protrudingeyesdegrees，thyroidfunction，liverfunction，bloodroutineexaminationandsoon.Results：Aftercured,theclinicalsymptoms，heartrate，weight，BMR，thyrocele，protrudingeyesdegrees，thyroidfunction，liverfunction，bl

7、oodroutineexaminationandsoonwereobviouslyimproved，whichshowedsignificantdifferencefromthecontrolgroup.Duringthetestsadversereactionsdidnotappear.Conclusion:YiQiYangYinQingGanFanghascurativeeffectonQiandYindeficiency,syndromeofGravesDisease,whichcanimprovespatientsclinicalsym

8、ptoms，heartrate，weight，BMR，thyrocele，protrudingeyesdegrees，thyroidfunction，