mri在乳腺病变诊断中应用价值研究

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1、山东人学硕十学位论文2．1DCE-MR／：Fordynamiccontrast-enhancedMRimaging．TIhighresolutionisotropicvolumeexcitation(THRIVE)sequenceWasusedinthetransverseplane．TheunenhancedT1weightedimagingWasfollowedby15dynamiccontrast—enhancedsequences。aftertheintravenousbolusinjectionofO．15mmol／kgbodywei

2、ghtofGD—DTPA(Magnevist)intoadorsalveinofhandattherateof2．5ml／sanda15mlsalinesolutionflushattherateof2．0ml／s．2．2DWI：Echoplanarimaging(EPI)sequenceWasperformedonfourbvalues(125s／mnl2，250s／nun2，375s／mm2and500s／mm2)withtheparametersaSfollows：repetitiontime(TR)／echotime(TE)，2500m

3、s／62ms；slicethickness，4mm；slicegap，lmm；fieldofview,220mmx220mm；matrix，126x240；scantime，137s．3．Evaluationmethods：3．1DCE—MR／：Weacquiredthebreastlesions’morphologicfeatures，time．signalintensitycurve(TIC)andearlyenhancementraterespectively．Accordingtotheirshapes，TICWasclassified

4、intotypeI，typeIIandtypeIII．TypeIissteadyenhancement．TypeIIisplateauofsignalintensity．TypeIIIiswashoutofsignalintensity．3．2DWI：DWIWasobtainedfromtheworkstation．TheADCvalueswerecalculatedaccordingtoADC=【In(S2／S1)]／(b2一b1)，whereSIandS2arethelowandhighsignalintensitiesintheregio

5、nsofinterest(ROI)obtainedwithdifferentbvalues(125---,0，250"--0，375"--0，500---0s／mm2)．4．Statisticalassay：TheStudentt-testWasusedtotestthesignificancebetweentheenhancementratesofbenignandmalignantlesions．Andthet．testwasusedtotestthesignificanceofthecurvetypedistributionsontheb

6、enignandmalignantlesions．One·wayANOVAandSNK(Student-Newman—Keuls)wereusedtoanalyzethedifferencesamongthemeanADCvaluesofthemalignantlesions，benignlesionsandnormalfibroglandulartissue．ThedatawasanalyzedusingthesoftwareofSPSS11．0，P<0．05Wasusedtoindicatesignificance．Results：1．48

7、breastlesionswererevealedonMRimagingin39casesincludingsolitarylesionsin33cases，multiplelesionsin6cases．Ofmultiplelesions，unilateralmultiple6山东人学硕士学位论文lesionsin4cases，bilateralmultiplelesionsin2cases．31lesionsin26casesweremalignant．17lesionsin13caseswerebenign．Alllesionswerei

8、dentifiedbyhistopathology．2．MostofthebreastlesionswerelowsignalintensityonT