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《种黄连生物碱的抑菌作用（antibacterial activity of alkaloids from coptis chinensis）》由会员上传分享，免费在线阅读，更多相关内容在教育资源-天天文库。
1、4种黄连生物碱的抑菌作用（Antibacterialactivityof4alkaloidsfromCoptischinensis）Antibacterialactivityof4alkaloidsfromCoptischinensis[Objective]berberine,HuangLianjian,andpalmatineare4mainkindsofCoptischinensisInordertostudythedifferenceofantibacterialpropertiesof4alkaloidsfromCoptischinensis,theinhibitionoft
2、hemwasstudiedinthisexperimentThespectrumandantibacterialactivitywerestudied.Methods4alkaloidsextractedfromtherhizomeofCoptischinensiswereusedastheexperimentThe19commonmicroorganismsweretestedundertheconcentrationof2000Mg/raLsolutionbythemethodofbacteriostaticcircleThedrugsensitivitytestwascarri
3、edout,andtheminimalinhibitoryconcentration(MIC)ofsensitivebacteriawasdeterminedbyturbidimetryTesting。Resultsthesensitiverangeofthe4alkaloidswasthesame,buttheantibacterialactivitywasdifferent,amongwhichberberinewasthemostsensitiveTheantibacterialactivitywasthehighest,followedbyHuangLianjianandBa
4、ma,andthealkaloidwastheleast;the4alkaloidsofCoptischinensisweregrampositiveTheinhibitoryactivityofthebacteriawasgreaterthanthatofGram-negativebacteriaandyeasts;eachalkaloidwasresistanttotheresistantStaphylococcusaureus(MR)TheantibacterialabilityofStaphylococcusaureuswasbasicallythesame.Conclusi
5、onthe4alkaloidsofCoptischinensisareantibacterialconstituentsofCoptischinensisfranch,Theantibacterialspectrumwasthesame,buttheantibacterialactivitywasdifferent;theresistanceof4kindsofCoptisalkaloidstothedrug-resistantstaphylococcusaureusIthaseliminationeffect.[keyword]Coptischinensisberberine,pa
6、lmatine,berberine,bacteriostasisAbstract:ObjectiveBerberine,jatrorrhizine,palmatine,andCoptisinearefourleadingalkaloidsfromCoptidisrhizome.ToResearchthecharacteristicsofantimicrobialactivityofaboveAlkaloids,theantimicrobialspectrumsandabilitiesofthemwereDeterminedinthispaper.MethodsSensitivitie
7、sof19microorganismstoBerberine,jatrorrhizine,palmatine,andcoptisinewerestudiedunderMedicineconcentrationof2000
8、Jg/mlbyantimicrobialcircleExperimentandtheirMinimumInhibitoryConcentrations(MIC)against14sensitivemicroorganismsweredet
