应变率成像技术定量评价原发性高血压患者左房功能的价值

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1、南昌大学医学院硕士学位论文应变率成像技术定量评价原发性高血压患者左房功能的价值姓名：肖小鹏申请学位级别：硕士专业：影像医学与核医学指导教师：邓林云20090501摘要高血压I组，差异均有统计学意义(尺0。05)，而高血压Ⅱ组SRa明显大于健康对照组(氏O．01)；5．SRa值与传统评价左房功能指标(L虹)呈显著正相关(r=O．85，P<0．01)。结论：应变率成像技术(SRI)能定量评价原发性高血压患者的左房功能，其作为定量评价左房功能的一项新技术，为更早反映原发性高血压患者的左室舒张功能的改变提供了一种新的

2、思路。关键词：应变率成像技术；原发性高血压；左房功能AbstractObjective：Toinvestigatethevalueofstrain-rateimaging(SRI)inleftatrialfunctionevaluationinpatientswithessentialhypertension．Methods：Patientsweredividedintohealthycontrolgroup，hypertensiongroupI(normaldiameterofleftatrialgroup

3、，theleftventricularendsystolicleftatrialdiameter(LAD)<3．6cm)andhypertensiongroupU(1eftatrialexpansiongroup，LAD>-3．6cm)．Thereare80cases，88casesand85casesinhealthycontrolgroup，hypertensiongroupIandhypertensiongroupIIrespectively,atanaverageoldof60．114-5．85，61

4、，224-4．93，62．984-5．89．LAD，leftatrialmaximumvolume(LAESV)，leftatrialvolumebeforethebeginningofcontraction(LAPV)，leftatrialminimalvolume(LAEDV)，calculatingtheleftatrialstrokevolume(LASV)weremeasuredbyPhilipsiE33colorDopplerultrasoundimagingdevice(TheNetherlan

5、ds)．MitralflowvelocityE，A，E／A，mitralannulardiameter(d)，leftventricnlarejectionfraction(LVEF)，mitralApeakpoints(AVTI)andmitralvalveflowtotalscore(TVTD，calculatetheleftatrialfillingfraction(LAFF)，thespectrumofpulmonaryvenoussystolicanddiastolicpeakvelocityrat

6、ioofpeakvelocity(S／D)，leftatrialejectionforce(LAF)wererecordedonapicalfour-chamber．LeftatrialstrainratewasanalyzedbyQLA8softwareinTDImode．Theleftatrialsystoleatrialseptal，leftatrialposteriorwallpeakstrainrateandtheiraverage(SRa)werecalculatedafterobtaininga

7、trialseptalandposteriorwalIofleftatrialstrainratectlr'v'e．DataWasanalyzedbySPSS13．0statisticalsoftware，includingmulti—groupcomparison，one．wayANOVAandPearsoncorrelationanalysis．氏O，05valueWasconsideredtobestatisticallysignificant．Results：1．LVEFsinthehealthyco

8、ntrolgroup，hypertensivegroupI、hypertensivegroupIIhavetlOstatisticallysignificantdifference(P>0．05)．E／AandS／DinthehealthycontrolgroupwithhypertensivegroupIhavenosignificantdifference(P>O．05)，whileE／Ainh