冠心病与血脂异常相关性

《冠心病与血脂异常相关性》由会员上传分享，免费在线阅读，更多相关内容在行业资料-天天文库。

1、心血管康复医学杂志2012年12月第21卷第6期ChinJCardiovascRehabilMed，December2012，Vol21No．6575·康复论著·CorrelationbetweencoronaryheartdiseaseanddyslipidemiaHEXin，LIUZhi-yong，LIUJing-yan，YUANXu-ming，SHENCheng-zhi，TANGYan-fang，PENGYi-ming，LIUWei。WANGLei／／DepartmentofCardiology，PeoplesHospitalofLiu

2、yangCity，Changsha，Hunan，410300，ChinaCorrespondingauthor：WANGLei，E-mail：w11318@163．eomAbstract：0bjective：Tostudyrelationshipbetweencoronaryheartdisease(CHD)anddyslipidemia．Methods：Ato-talof302CHDpatientsdiagnosedbycoronaryangiographywereenrolledasCHDgroup，and218healthysnbjec

3、tswithoutcardiovascularandcerebrovasculardiseasesbyhearthexaminationwereregardashealthycontrolgroup．Relativedatawerecollectedandlevelsofbloodtriglyceride(TG)，totalcholesterol(TC)，highdensitylipoproteincholesterol(HDL·C)andlowdensitylipoproteincholesterol(LDL—C)weremeasured，

4、andcomparedbetweentwogroups．Results：Comparedwithhealthycontrolgroup，thereweresignificantincreaseinlevelsofbloodTC[(4．03±O．97)mmol／Lvs．(4．62±1．06)mmol／L]andLDL—C[(2．51±0．86)mmol／Lvs．(3．76：4-1．07)mmol／L]inCHDgroup，P<0．01both．MultiplefactorLogisticregressionanalysisindicatedth

5、atelevatedLDL-ClevelwasanindependentriskfactorforoccurrenceofCHD(OR一2．608，95％CI一1．268—5．366，P一0．009)．Conclusion：TheresultsshowthatlevelsofTCandLDL—Cinpatientswithcoronaryheartdiseasearesignificantlyhigherthanthoseofhealthycontrolgroup．ElevatedLDLlevelmaybeanindependentriskf

6、actorforoccurrenceofcoronaryheartdisease．Keywords：Coronaryarterydisease；Hyperlipidemia；RiskfactorsArticlehumbet1008．0074(2012)06．575．04Doi：10．3969／j．issn．1OO8—0074．2012．06．03冠心病与血脂异常的相关性／何昕，刘智勇，刘景艳，袁旭明，谌承志，唐艳芳，彭一鸣，刘伟，王磊／／湖南省测阳市人民医院心内科，湖南长沙410300通信作者：王磊，E-mail：w11318@163．com

7、摘要：目的：研究冠心病与血脂异常的相关性。方法：选择冠脉造影检查确诊的冠心病患者302例(CHD组)，门诊体检无心脑血管疾病的健康人群218例(健康对照组)，收集所有研究对象相关资料，测定其血甘油三酯(TG)、总胆固醇(TC)、低密度脂蛋白一胆固醇(LDL)、高密度脂蛋白一胆固醇(HDL-C)含量，并进行对比分析。结果：与健康对照组比较，CHD组血TC[(4．03士0．97)mmol／L比(4．62±1．06)mmol／L]、LDL-C[(2．51士0．86)mmol／L比(3．76士1．07)mmol／L]水平明显升高(P均<0．O1)。多

8、因素Logistic回归分析显示，LDL．C水平升高是冠心病发生的独立危险因素(OR一2．608，95％CI一1．268—5．366；P一0．009)。结论：本研究