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1、胆汁反流性W炎临床治疗分析［摘要］目的：探讨多潘立酮（吗丁咻）和铝碳酸镁联合用药治疗胆汁反流性胃炎的临床疗效。方法：将我科2006年2月〜2009年6月收治的148例胆汁反流性胃炎患者随机分为治疗组和对照组，各74例。治疗组74例，口服多潘立酮片10mg,3次/d,餐前15min服药，铝碳酸镁0.5g,3次/d,餐后1h服用，治疗4周。对照组74例，口服铝碳酸镁0.5g,3次/d,餐后lh服用，治疗4周。分别于治疗前及治疗4周后记录上腹痛、饱胀、恶心、呕吐症状的积分，予以对比观察，疗程结束后复查胃镜。结果:治疗组临床疗效总有效率为94.6%,对照组总有效率为78.3%；胃镜征
2、象疗效分别为89.2%.70.3%o治疗后两组患者的症状均有减轻，治疗组减轻明显优于对照组。结论：多潘立酮可减少胃内胆汁反流，铝碳酸镁可结合胆酸，两者联合用药治疗胆汁反流性胃炎疗效显著，值得推广应用。［关键词］胆汁反流性胃炎；多潘立酮；铝碳酸镁［中图分类号］R573E文献标识码］A［文章编号］1673-7210(2010)02(b)—044—02Clinicalanalysisinthetreatmentofbile-refluxgastritisQIUWeidong(DepartmentofEmergeney,theQishiHospitalofDongguanCity,G
3、uangdongProvince,Dongguan523500,China)[Abstract]Objective：Toexploretheclinicalefficacyofdomperidone(Mot订ium)combinedwithaluminummagnesiumcarbonateinthetreatmentofbilerefluxgastritis.Methods：148casesofpatientswithbilerefluxgastritisfromFebruary2006toJune2009inourdepartmentwererandomlydivided
4、intotreatmentgroup(74cases)andcontrolgroup(74cases)・Thetreatmentgroup(74cases),domperidonetablets10mg,oral3times/day,fastin£for15minutesonmedication,aluminummagnesiumcarbonate0.5g,3times/day,takenonehourafterthemeal,treatmentfor4weeks・Inthecontrolgroup,74casesoforalaluminummagnesiumcarbonat
5、e0.5g,3times/day,takenonehourafterthemeal,treatmentfor4weeks,Respectively,beforetreatmentandtreatmentfor4weeksaftertherecordofabdominalpain,fullness,nausea,vomiting,symptomsofpointstobecomparativestudy,afterthereviewofendoscopictreatment・Results：Theclinicalefficacyofthetreatmentgroup,thetot
6、aleffectiveratewas94.6%,thetotaleffectiverateofthecontrolgroupwas78.3%,endoscopicsignsofefficacywere89.2%,70.3%.Aftertreatmentofpatientswithsymptomsofbothgroupswerereducedsignificantly,butthetreatmentgroupwasbetterthanthecontrolgroup・Conclusion：Domperidonecanbereducedintragastricbilereflux,
7、aluminummagnesiumcarbonatecanbecombinedacid,bothofcombinationtherapyintreatingbilerefluxgastritisissignificant,andtobeworthyofpromotion._Keywords]Bilerefluxgastritis；Domperidone；Hydrotaleite胆汁反流性胃炎（BRG）是由器质性因素（手术等）或非器质性因素（神经、体液、肌肉等）造成胃幽门功能失常致胆汁反流入胃，是消化内科
