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1、中国矫形外科杂志2005年6月第13卷第12期OrthopJChin,Vol.13,No.12June2005·915··实验研究·间断拔钉对股骨颈骨折愈合的影响姚双权张英泽张奉琪潘进社吴希瑞彭阿钦王鹏程摘要目的:探讨间断拔钉对股骨颈骨折愈合的影响。方法:取本地自然放养的健康成年山羊18只,建立双侧股骨颈骨折后3枚加压螺纹钉固定的模型,随机取样的一侧为实验侧,分别于术后4、8、12周各拔1钉;另一侧为对照侧,术后12周时3枚钉一起拔出。模型建立后随机分为A、B、C3组,分别于术后8、12、16周处死取材。期间做X线检查、核素骨显像、组织学检查对比两侧愈合情况有无差别。结果:骨同位素
2、显像血流相及血池相显示A、B组实验侧动脉灌注及静脉回流较对照侧通畅,静态相显示实验侧血运优于对照侧。组织学观察结果显示:在血管生成、编织骨生成、坏死骨清除等阶段实验侧均较对照侧提前。结论:应用间断拔钉法治疗股骨颈骨折,可改善股骨头血运,加快股骨颈骨折愈合。关键词间断拔钉;股骨颈;骨折;愈合中图分类号R683文献标识码A文章编号1005-8478(2005)12-0915-03Researchoftheeffectofdrawingoutthescrewsintermittentlyonthehealingoffemoralneckfracture∥YAOShuang2quan,ZH
3、ANGYing2ze,ZHANGFeng2qi,etal.OrthopedicResearchInstituteofTheThirdHospitalofHeBeiMedicalUni2versity,ShijiazhuangHebei050051AbstractObjective:Tostudytheeffectofdrawingoutthescrewsintermittentlyonthehealingoffemoralneckfracture.Method:Eighteenhealthygoatswithmaturedskeletonwereusedtomakethemodel
4、offemoralneckfracturefixedwiththreecom2pressionscrews.Onesidewasselectedrandomlytobetheexperimentalsideandthethreescrewsweredrawnoutrespectivelyinthe4th,8th,12thweekaftertheoperation.Theothersidewasthecontrolsideandthethreescrewsweredrawnoutinthe12thweekaftertheoperationtotally.Afterthemodelwa
5、smadetheyweredividedintoA,B,Cgroups,whichweresacrificedseparatelyinthe4th,8th,12thweekaftertheoperation.TtheexperimentalsidewascomparedwiththecontrolsideonXray,SPECT,andmicroscopicinspection.Result:ThedataofSPECTappears:thebloodflowinthearteryandtheveinoftheexperimentalsidewasbetterthanthatoft
6、hecontrolsideingroupA,B.TherewasnodifferencebetweenthetwosidesingroupC.Themicroscopicin2spectionshowed:Thegenerationofnewbloodcapillaryandinterlacedboneintheexperimentsidewasmorerapidthanthatofthecontrolside.Theclearanceofnecrosisbonechipsintheexperimentsidewasaccelerated.Conclusion:Drawingout
7、screwintermit2tentlycanimprovethebloodflowoftheferaoralheadandfacilitatethehealingofthefracture.Keywordsdrawingoutthescrewsintermittently;Femoralneck;Fracture;Healing股骨颈骨折是临床上常见的一种骨折,随着社会的进1材料与方法步,人均寿命延长,人口老龄化和交通、建筑业的发展,股1.1实验动物及分组[1]骨颈
