中药当归饮子联合盐酸西替利嗪治疗慢性荨麻疹的疗效观察.pdf

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1、·4102··中医·中西医结合研究·中药当归饮子联合盐酸西替利嗪治疗慢性荨麻疹的疗效观察石春蕊，陈康兵，王敏，匡钱华，张鸫媛，毛鹤，任万明【摘要】目的了解中药3"-归饮子、盐酸西替利嗪及二者联合用药治疗慢性荨麻疹的疗效。方法半随机将确诊为慢性荨麻疹的75例患者分为中药组、西药组及中西医结合组。中药组服用中药当归饮子，2&Jd；西药组服用盐酸西替利嗪10mg，1&／d；中西医结合组同时服用当归饮子和盐酸西替利嗪，疗程均为28d。治疗期间第2周、第4周进行疗效评价，治疗结束后第3个月、第6个月进行随访调查复发情况。结果治疗后第2周、第4周、第3个月、第6个月症状积分下降指数3组间差异有统计学意

2、义(P<0．05)。联合治疗后第2周，中西医结合组瘙痒评分优于中药组、西药组，3组间差异有统计学意义(P<0．05)。不同方案治疗慢性荨麻疹疗效间差异有统计学意义(P

3、利嗪治疗慢性荨麻疹的疗效观察[J]．中国全科医学，2013，16(12)：4102—4105．[ww．chinagp．net]EfectofChineseAngeHcaDecoctionPlusCetirizineHydrochlorideinTreatmentofChronicUrticariaSHIChun—rui，CHEN一bing，WANGMin，eta1．TheFirstHospitalofLanzhou，Lanzhou730000，China【Abstract】0bjectiveToobservetheclinicalcurativeefectsofChineseangelic

4、adecoction，Cetirizinehydrochloride，andtheirintegratedremedyfortreatmentofchronicurticaria．MethodsTotally75pailentswithchronicurtieariawererandomlydividedintothreegroupsofA，B，andCtreatedwithtraditionalChinesemedicine(Chineseangelicadecoction，twiceaday)westernmedicine(Cetirizinehydrochloride，10mgdai

5、ly)，andtheintegratedremedy(ChineseangelicadecoctionplusCetiriz—inehydrochloride)respectively．Thecoursewasfourweeks，andthecurativeeffectswereevaluatedatthesecondandfourthweek．Thepatientswerefolloweduptosurveyrelapseratesinthethirdandsixthmonthaftertheendofthetreatment．ResultsAtthesecondandfourthwee

6、ks，andinthethirdandsixthmonthsaftertheendofthetreatment，therewasstatisticallysignificantdifferenceinreducingindexofsymptomscorebetweenthethreegroups(P<0．05)．Atthesecondweeks，theaveragepruritusscorewasbetterinthegroupCthaninthegroupAandB(P<0．05)．Thestatisticallysignificantdiferenceinefectwasfoundam

7、ongthethreedifferentremedies(P<0．05)，withtheeffectofgroupCwasbetterthatthoseoftheothertwogroups，andtheRiditvalueswere0．6116，0．4947，0．3993，respectively．ConclusionTheintegratedremedyofChineseangelicadecoctionandCet