CT灌注成像评价经导管动脉化疗栓塞术治疗原发性肝癌的疗效-论文.pdf

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1、中国介入影像与治疗学2013年第10卷第12期ChinJIntervImagingTher，2013，Vol10，No12EvaluationoftherapeuticeffectoftranscatheterarterialchemoembolizationforprimaryhepaticcarcinomawithCTperfusionimagingQIUGuo—qin，XULi—zhen，CHENYu—qiang，LJUChang—hua(CancerCenter，ChenggongHospital

2、Al；tliatedtoXiamenUniversity，the174thHospitaloftheChinesePeople'sLiberationArmy，Xiamen361003，China)[Abstract]0bjectiveToexplorethevalueofcTperfusionimaging(CTPI)using320一rOWcTscannerinevaluationonthetherapeuticeffectofTACEforprimarylivercancer(PHC)．Method

3、sTotally91patientswithadvancedPHCunder—wentCTPIbeforeandafterTACE．ComparedwiththeresultofDSA，bloodperfusionchangesoftumorandnormalliverwereobserved，andthecurativeeffectofTACEwasevaluated．ResultsCTPIcorrespondedwithDSA。thediagnosticcO—incidencerateofCTP1wa

4、s100．Bloodflow(BF)，bloodvolume(BV)，hepaticarteria1persusion(HAP)andhepaticperfusionindex(HPI)oftumortissuedecreasedafterTACE(allP<0．05)，whilenostatisticallysignificantdifferenceofmeantransittime(MTT)，probabilityofsurfaceareaproduct(PS)norportalveinperfusi

5、on(PVP)oftumortissuewasfoundbeforeandafterTACE(allP>0．05)．Unevenmelanomafocaliodineoildepositsandbloodperfusionwereshowedin59caseswithresidua1tumortissue，withBF，BV，HAP，HPI，PSofresidualtumortissuehigherbutMTTandPVPlowerthanthosenormalhepatictissue(allP<0．0

6、5)．ConclusionCTPIusing320一rOWCTscannercancomprehensively．derectlyandquantificationallyreflectthehemodynamicchangesofPHCbeforeandafterTACE，thereforeobjectivelyandcorrectlyevaluatingtheeffectofTACE．[Keywords]Liverneoplasms；Perfusionimaging；Tomography，x—rayc

7、omputedCT灌注成像评价经导管动脉化疗栓塞术治疗原发性肝癌的疗效邱国钦，许丽贞，陈玉强，刘昌华(厦门大学附属成功医院中国人民解放军第174医院肿瘤中心，福建厦门361003)[摘要]目的探讨320排CT灌注成像(CTPI)评价TACE治疗原发性肝癌(PHC)疗效的价值。方法对91例中晚期PHC患者于TACE治疗前后行CTPI，对比DSA结果，观察TACE前后肿瘤与正常肝组织的血流灌注参数的变化，评价TACE疗效。结果CTPI诊断结果与DSA结果相符，诊断符合率为100，TACE后肿瘤组织的肝血流量(

8、BF)、肝血容量(BV)、肝动脉灌注量(HAP)、肝动脉灌注指数(HPI)均较术前降低(P均o．05)；59例瘤灶碘油沉积不均，灌注图显示存在血流灌注，其残瘤组织的BF、BV、HAP、HPI、PS值均高于正常肝组织(P均