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1、MyoepitheliomaoftheParotidGland:CTImagingfindingsHuanhuanSu2012-02-06MEisabenignsalivaryglandtumorcomposedalmostexclusivelyofsheets,islands,orcordsofcellswithmyoepithelialdifferentiationSpindlecells,plasmacytoidcells,epithelioidcells,clearcellpatterns.Othertermsmyoepith
2、elialadenomabenignmyoepithelialtumorIntroductionBenignadenomasaccountfor65.5%ofsalivaryglandtumors.MEswererecognizedasahistologicallydistinctentityin1991bytheWorldHealthOrganization.IntroductionMEsaccountfor1.5%ofallofthetumorsinthemajorandminorsalivaryglands,and40%aris
3、eintheparotidglands.Minorsalivaryglandsfollowinfrequency,especiallyinthepalate(21%).IntroductionTheageofpatientswithMErangesfrom9to85years,withanaverageof44yearsandthepeakageofoccurrenceinthethirddecade.Ittypicallypresentsasasolitary,slowlygrowing,otherwiseasymptomaticm
4、ass.MEsarelesspronetorecurthanpleomorphicadenomas.IntroductionCTimagingfeaturesandpathologyCTimagingfeatureshomogenousenhancement(Fig1)inhomogeneousenhancementwithenhancingnodules,thepresenceofcysticareas(Fig2),slitlike-shapedarea(Fig3),andlinearbands(Fig4).smoothorlobu
5、latedcontourslocatedinthesuperficiallobeoftheparotidgland,abuttedthecapsuleoftheglandCTimagingfeaturesandpathologyA62-year-oldwomanwithME.A,PrecontrastaxialCTscanshowsaround,well-definedmass(27.39HU)inthesuperficiallobeoftherightparotidglandabuttingonthecapsuleofgland(a
6、rrow).B,Contrast-enhancedaxialCTscanshowsthemass(102.11HU)withhomogeneousstrongenhancement(arrow).C,Microscopicexamination(HE×2)showsthattheME(M)isseparatedfromtheparotidglandandthesurroundingsofttissuesbyafibrouscapsule(FC).Thestromaisscanty.D,Microscopicexamination(HE
7、×100)showsthatthetumoriscomposedoftheplasmacytoidandspindlecells.Relativelylargevesselsareseeninthetumor(arrows).CTimagingfeaturesandpathologyA66-year-oldwomanwithME.A,PrecontrastaxialCTscanshowsanindistinctmarginmassinthesuperficiallobeoftheleftparotidglandabuttingonth
8、ecapsuleoftheglandwithcalcification(arrow).B,Contrast-enhancedaxialCTscanshowsthemasswithinhomogeneousenhancem