尘螨疫苗治疗对呼吸道天然免疫调节机制的研究

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1、中图分类号tR89;R36«,R39尘蹒疫苗治疗对呼吸道天然免疫调节机制的研究院（系)、所临庆医学院研宄生姓名干1梅轶学科、专业内科学导师姓名李国平教持二〇—五年四月1目录尘螨疫苗治疗对呼吸道天然免疫调节机制的研究.........................................1摘要................................................................................................................4前言.....................

2、.......................................................................................11材料与方法........................................................................................................14实验器材与仪器................................................................................

3、................14主要实验试剂....................................................................................................14主要溶液配制....................................................................................................17主要实验仪器...............................................

4、.....................................................17试验方法............................................................................................................18统计学处理........................................................................................................32结果.....

5、.......................................................................................................33(1)尘螨疫苗减轻尘螨诱导的小鼠哮喘...........................................................33(2)尘螨疫苗减轻哮喘小鼠肺部绿脓杆菌感染...............................................34(3)尘螨疫苗上调哮喘小鼠呼吸道CRAMP表达..........

6、.................................36(4)TGF-β1增加CYP27b1表达而增高HBE细胞表达CAMP.....................36(5)尘螨疫苗上调哮喘小鼠肺部CYP27b1蛋白表达.....................................39附：图表............................................................................................................40讨论..............

7、..............................................................................................54结论............................................................................................................602参考文献.................................................................