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时间:2020-04-19
《骨科创口感染患者血清炎性指标变化研究.pdf》由会员上传分享,免费在线阅读,更多相关内容在应用文档-天天文库。
1、·4322·中华医院感染学杂志2014年第24卷第17期ChinJNosocomiolVo1.24No.172014doi:10.11816/cn.ni.2014—134054论著●骨科创口感染患者血清炎性指标变化研究李文华,余玲玲,张雪霞。,唐宇新,周少朋。,陈红涛(1.中山大学附属第五医院检验科2.放疗科3.麻醉科4.骨科,广东珠海519000)摘要:目的探讨研究骨科创口感染患者血清炎性指标的变化情况,为临床诊断与治疗提供依据。方法选取2011年7月一2013年6月进行治疗的32例骨科创口感染患者为A组,32例骨科无创口感染者为B组,32名健康人为C组,将3组血清白介素8(IL
2、一8)、肿瘤坏死因子~(TNF—a)、降钙素原(PCT)及C一反应蛋白(CRP)阳性率与含量进行比较,同时比较A组中浅层感染与深部感染者的阳性率和含量。结果A组的血清IL一8、TNF-a、PCT及CRP阳性率分别为93.75、9O.63、93.75和9O.63,血清含量分别为(16.49士2.56)pg/ml、(3.45-4-0.40)ng/ml、(7.86±1.15)g/I和(15.44士2.30)mg/L,均高于B组与C组,B组则高于C组,且A组中深部感染者高于浅层感染者,差异有统计学意义(尸3、康人,且深部感染者表现更为明显。关键词:骨科;创口感染;血清炎性指标;变化中图分类号:R181.32文献标识码:A文章编号:1005-4529(2014)17—4322—03StudyonchangesofseruminflammatoryindexesofpatientswithwoundinfectionsindepartmentoforthopedicsLIWen—hua,YULing—ling,ZHANGXue—xia,TANGYu—xin,ZHOUShao—peng,CHENHong—tao(TheFifthAffiliatedHospitalofSunYat—senUn4、iversity,Zhuhai,Guangdong519000,China)Abstract:OBJECTIVEToexplorethechangesofseruminflammatoryindexesofpatientswithwoundinfectionsindepartmentoforthopedicssoastoprovideguidanceforclinicaldiagnosisandtreatment.METHODSFromJul2011toJun2013,totally32patientswithwoundinfectionswhoweretreatedinthede5、partmentoforthopedicswereas—signedasthegroupA,32patientswithoutwoundinfectionsasthegroupB,32healthypeopleasthegroupC;thepositiveratesandcontentsoftheseruminterleukin一8(IL一8),tumornecrosisfactora(TNF-a),procalcitonin(PCT),andC—reactiveproteinwereobservedandcomparedbetweenthethreegroups;theposit6、iveratesandcon—tentswerecomparedbetweenthepatientswithsuperficialinfectionsandthepatientswithdeepinfectionsinthegroupA.RESULTSThepositiveratesoftheserumIL一8,TNF-a,PCT,andCRPofthegroupAwere93.75,9O.63,93.75,and90.63,respectively;theserumcontentswere(16.49±2.56)pg/ml,(3.454-0.40)ng/m1,(7.86士1.157、)/~g/L,and(15.44_-4-2.30)mg/L,respectively;boththepositiveratesoftheserumIL一8,TNF-a,PCT,andCRPandtheserumcontentsofthegroupAwerehigherthanthoseofthegroupBandthegroupC;inthegroupA,thepositiveratesoftheserumIL一8,TNF_a,PCT,andCRPandtheseru
3、康人,且深部感染者表现更为明显。关键词:骨科;创口感染;血清炎性指标;变化中图分类号:R181.32文献标识码:A文章编号:1005-4529(2014)17—4322—03StudyonchangesofseruminflammatoryindexesofpatientswithwoundinfectionsindepartmentoforthopedicsLIWen—hua,YULing—ling,ZHANGXue—xia,TANGYu—xin,ZHOUShao—peng,CHENHong—tao(TheFifthAffiliatedHospitalofSunYat—senUn
4、iversity,Zhuhai,Guangdong519000,China)Abstract:OBJECTIVEToexplorethechangesofseruminflammatoryindexesofpatientswithwoundinfectionsindepartmentoforthopedicssoastoprovideguidanceforclinicaldiagnosisandtreatment.METHODSFromJul2011toJun2013,totally32patientswithwoundinfectionswhoweretreatedinthede
5、partmentoforthopedicswereas—signedasthegroupA,32patientswithoutwoundinfectionsasthegroupB,32healthypeopleasthegroupC;thepositiveratesandcontentsoftheseruminterleukin一8(IL一8),tumornecrosisfactora(TNF-a),procalcitonin(PCT),andC—reactiveproteinwereobservedandcomparedbetweenthethreegroups;theposit
6、iveratesandcon—tentswerecomparedbetweenthepatientswithsuperficialinfectionsandthepatientswithdeepinfectionsinthegroupA.RESULTSThepositiveratesoftheserumIL一8,TNF-a,PCT,andCRPofthegroupAwere93.75,9O.63,93.75,and90.63,respectively;theserumcontentswere(16.49±2.56)pg/ml,(3.454-0.40)ng/m1,(7.86士1.15
7、)/~g/L,and(15.44_-4-2.30)mg/L,respectively;boththepositiveratesoftheserumIL一8,TNF-a,PCT,andCRPandtheserumcontentsofthegroupAwerehigherthanthoseofthegroupBandthegroupC;inthegroupA,thepositiveratesoftheserumIL一8,TNF_a,PCT,andCRPandtheseru
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