黄芪建中汤加减方合优甲乐治疗桥本甲状腺炎的临床疗效观察

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1、提要目的：观察黄芪建中汤加减方配合优甲乐治疗桥本甲状腺炎早期（临床指标FT3、FT4、TSH正常或仅TSH偏高，而A-TPO、A-TG明显升高），证属脾虚痰气瘀互结型的临床疗效，并探讨中西医结合的治疗优势。方法：将临床诊断为桥本甲状腺炎证属脾虚痰气瘀互结型的60例患者随机分为两组，治疗组30例予以黄芪建中汤加减方配合优甲乐治疗；对照组30例予优甲乐治疗，用药4周为一个疗程，连续3个疗程。结果：临床观察表明，治疗组在改善本病症状和体征方面明显优于对照组（P<0.05）；在改善A-TPO、A-TG方面明显优于对照组（P<0.01）；在改善

2、甲状腺左右叶、峡部厚度方面优于对照组（P<0.05）。并且临床用药安全，未发生不良反应。结论：临床疗效显示黄芪建中汤加减方配合优甲乐治疗桥本甲状腺炎早中期临床疗效肯定，不良反应小，值得进一步探讨研究。关键词黄芪建中汤加减方；桥本甲状腺炎；临床研究TheClinicalObservationofModifiedHuangqiJianzhongDecoctiononTreatingtheHashimoto'sthyroiditisCooperatingwithEuthyroxSpeciality:InternalMedicineOfTCM

3、Author:ZouliyanTutor:ProfessorYangWenjunAbstractObjective:ToobservetheclinicalcurativeeffectthatModifiedHuangqiJianzhongDecoctionwithEuthyroxcausedintheearlyormiddletreatmentoftheHashimoto'sthyroiditiscausedbythedeficiencyofspleen(clinicalindicatorsFT3,FT4,TSHwasnormal,

4、whiletheA-TPO、A-TGwassignificantlyhigher),andtoexplorethetherapeuticadvantagescombingchineseandwestern.Method:60patientsdiagnosedbytheHashimoto'sthyroiditiscausedbythedeficiencyofspleenwererandomlydividedintotwogroups.Thetreatmentgroupof30casesweregiventheModifiedHuangq

5、iJianzhongDecoctionandeEuthyrox,theothersweregivenEuthyroxascontrolgroup.Druguse4weeksforaperiodoftreatment,3successivetreatment.Result:clinicalobservationshowsthatthetreatmentgroupinimprovingthediseasesymptomsandsignsisbetterthanthecontrolgroup(P<0.05);InimprovingA-TPO

6、,A-TGisbetterthanthecontrolgroup(P<0.01);Intheimprovementofleaves,theisthmusaboutthyroidthicknessbetterthancontrolgroup(P<0.05).Andclinicaldrugsafety,didnotproduceadversereactions.Conclusion:clinicalcurativeeffectshowstheclinicalefficacyofModifiedHuangqiJianzhongDecocti

7、onwithEuthyroxintheearlyormiddletreatmentofHashimoto'sthyroiditisissure，adversereactionssmallanddeservesfurtherinvestigationresearch.KeywordsModifiedHuangqiJianzhongDecoction;Hashimoto'sthyroiditis;Clinicalresearch目录引言....................................................

8、...........................................................................1临床研究..............................