微波诱导高温致兔脊髓损伤的实验分析

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1、军医进修学院硕士学位论文normalinhistopathology．GroupD：ThereweresomechangesofCSEPsuchasprolongedlatencyanddecreasedamplitudeaftermicrowavehyperthermia．Musclestrengthandsensationdecreaseafteroperation．Thewhitematterwasinlightedema,andthebrokennervefiberandsmalllesioncoul

2、dbeobservedoccasionally．Thequantityofthenervecellsinthegraymatterbecomesmall．Swellingneurons，shrinkingnucleusandpointhemorrhagecouldbeobserved．TheabovechangeswereobservedinHEstaining．Thequantityofneuronsstainedbynisslstainingbecamesmall，andnissl’Sbodydissol

3、ve．Thenormalneuronscouldbeobservedinnisslstaining．Theroughendoplasmicreticulumwasinderangement．Theshrinkingnucleusandloosenervefibercouldbeobservedbyelectronmicroscope．GroupE：ThewaveformofCSEPisnotenduedaftermicrowavehyperthermia．Musclestrengthbecamezero，an

4、dsensationdisappearafteroperation．Thespinalcordwasseriouslyinjury．Thebigareahemorrhageandbrokennervefibercouldbeobservedinwhitematter．Thequantityofthenervecellsinthe铲aymatterbecomeobviouslysmall．Karyolysis，necrosisandbigareahemorrhagecouldbeobservedinthegra

5、ymatter．TheabovechangeswereobservedinHEstaining．Thequantityofneuronsstainedbynisslstainingbecameobviouslysmallandnissl’Sbodydisappear．Thenecrosiscouldbeobservedinnisslstaining．Karyolysisandbrokennervefiberwereobservedbyelectronmicroscope．Conclusions：1．Heati

6、ngthevertebralbodywithmicrowaveandkeepingthetemperatureoftheepiduralspacehalfhour．44℃intheepiduralspaceisthehi曲esttolerabletemperatureofrabbitsfornormalspinalcordfunction．Itis45。Cintheepiduralspaceandkeepingthetemperaturehalfhourthatmakingthespinalcordincom

7、pleteinjury．Whenitexceedthehighesttolerablequantityofheat，themorethequantityofheat，themoreseriousthespinalcordinjury．2．ItisfeasibletomakeanimalmodelwhosespinalcordWasthermalinjurywitllmicrowaveantenna．3．ItisreliabletomonitorspinalcordfunctionbyCSEP,andthech

8、angeofCSEPiscorrelated、析tIlthedegreeofspinalcordinjury．Wecanroughlyjudge6军医进修学院硕士学位论文thedegreeofspinalcordinjury．TheCSEPamplitudeismoresensitivethanlatencyinjudgingspinalcordinjury．Keywords：Microwave；s