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1、磁共振成像2010年第1卷第5期ChinJMagnResonImaging,2010,Vol1,No5临床研究
2、ClinicalArticles艾滋病合并弓形虫脑病的影像学表现*黄 华,邓莹莹,陆普选,马 威,朱文科,杨根东,叶如馨作者单位:[摘要] 目的探讨AIDS合并弓形虫脑病的影像学表现及特征。方法收集广东省深圳市第三人民医院放射科,10例AIDS合并弓形虫脑病的临床及影像学资料,回顾性分析其头颅影像表现518020特点。结果10例AIDS合并弓形虫脑病患者中共发现颅内病灶30个,每个患者病灶数目2~7个不等;结节状或类圆形病灶共20个。CT平扫所有颅内病灶第一作者简介
3、:表现均为低密度影,增强扫描有7个病灶出现环形强化;MRT1WI表现为低黄华(1982-),男,硕士,住院医或等信号,T2WI为高信号,增强MRI有8个病灶呈环形强化,其中2个表现为++师。E-mail:hncz05hh@163.com“靶征”,比较CD4T淋巴细胞计数高于50cell/μl的患者和CD4T淋巴细胞计数低于50cell/μl的患者,发现前者更易出现环形或结节状强化(卡方检验,通讯作者:P=0.009)。结论AIDS合并弓形虫脑病颅内病灶影像表现为多发性,多累及大陆普选,E-mail:lupuxuan@126.com脑半球、基底节区及丘脑,病灶的形态多为结节状或
4、类圆形,在CD4+T淋巴细胞计数相对较高的患者注入对比剂后更易呈环形或结节状强化。收稿日期:2010-07-13[关键词]免疫缺陷病毒,人类;获得性免疫缺陷综合征;弓形虫病,脑;计接受日期:2010-08-25算机断层摄影术;磁共振成像中图分类号:R512.91;R445.2文献标识码:AImagingappearanceoftoxoplasmaencephalopathyinAIDSDOI:10.3969/j.issn.1674-8034.2010.05.008patients*HUANGHua,DENGYing-ying,LUPu-xuan,黄华,邓莹莹,陆普选,等.艾滋
5、病合并弓MAWei,ZHUWen-ke,YANGGen-dong,YERu-xin形虫脑病的影像学表现.磁共振成像,DepartmentofRadiology,ShenzhenThirdPeople'sHospital,Shenzhen518020,China2010,1(5):353-358.*Correspondenceto:LuPX,E-mail:lupuxuan@126.comReceived13Jul2010;Accepted25Aug2010AbstractObjective:Tocharacterizethecranialimagingfindingsoftox
6、oplasmaencephalopathyinAIDSpatients.MaterialsandMethods:Aretrospectivereviewof10humanAIDSpatientswithtoxoplasmaencephalopathywasperformed.Headcomputedtomography(CT)andmagneticresonanceimaging(MRI)werereviewed.Results:Therewere30lesionsfoundin10patients,thenumberoflesionsforeachpatientranged
7、from2to7,therewere20nodularorovallesionsamongthe30lesions.Beforecontrastinjection,allthelesionswerelowdensityonCT;afterintravenouscontrastinjection,therewere7lesionsshowedringenhancement.FortheMRI,alllesionswerepredominantlyhypointenseonT1-weightedimages,allthelesionswerehyperintenseonT2-we
8、ightedimages.Post-contrastimagingrevealed+ringenhancementin8lesions,including2targetenhancement.PatientswithCD4+Tlymphocytecountabove50cell/μlcomparedwithCD4Tlymphocytecountlessthan50cell/μlwasmorelikelywithringornodularenhancement(Chi-squaretest,P=0.009