资源描述：
《生儿机械通气与肺、脑损害的长期随访》由会员上传分享，免费在线阅读，更多相关内容在教育资源-天天文库。
1、新生儿机械通气与肺、脑发育及损害的随访及预防策略复旦大学儿科医院孙波2011新生儿随访学习班新生儿呼吸衰竭NRF临床转归占NICU收治危重病13%-20%病死率motality32%-25%23NICU(Pediatrics2008;121:e1115)全国55NICU(Pediatrics2011待发表)全国14NICU(Neonatology2011;100:)河北50%CPAPvs.CMV(trigger)IVH/ICH?PVL/WMD?CP?BPD/CLD?Followup?Background比较2004-2010年NRF多中心研究范围全国河
2、北全国年份(12个月)200420072008省/区/直辖市,n14124人均GDP,Yuan12,85019,36321,000NICU数231455NICU收治病例数,n13,07011,10035,817NRF,n1,7221,8756,864NRF发生率,%13.216.919.7收治病例数/NICU,n558793731NRF/NICU,n75134125范围全国河北全国胎龄wk35.2+4.035.0+4.034.9+4.0体重g2,316+8312,267+8042,314+819男/女,%75.5/24.572.3/27.770.6/2
3、9.4激素GA<35wk,%31.732.125(35)剖宫产,%43.855.655.3应用Surfactant比例,%16.628.726.8CPAPonly,%415142.1CPAP+CMV,%152227.1CMV,%442730.8HFOV,%2.71.55.1比较2004-2010年NRF多中心研究RDSNation-wideHebeiNation-wide %200420072008n(%ofHRF)602(35)881(47)3010(43.9)Survival66.267.376.2Surfactant3658.354.8Survi
4、val78.873.779.9Non-surf6441.745.2Survival63.558.671.8Delta-survival15.315.18.1RDS<1500gNationHebeiNation-wide %200420072008n242331816Survival54.545.356.9Surfactant43.443.264.2Survival67.654.559.8Non-surf56.656.835.8Survival44.542.752.2Delta-survival13.111.87.6NICUdistributioninN
5、RFstudyMid-westernn=8South-easternn=15河北省ChinaGDPandpopulation(2007)GDP(USD)Population(×106)ShanghaiBeijingTianjinZhejiangJiangsuGuangdongShandongNeimengLiaoningFujianHebeiHeilongjiangJilinXinjiangShanxiHenanHubeiChongqingHainanHunanShanxiQinghaiNingxiaJiangxiSichuanXizangGuangx
6、iAnhuiGansuYunnanGuizhouWithGDPatmidlevelPopulation:650million(50%)PopulationGDP(1USD=7.5CNY)ParticipationcentersinHebeicentralcitiesZhangjiakouChengdeQinhuangdaoTangshanBaodingLangfangShijiazhuangCangzhouHengshuiXingtaiHandanBeijingTianjinCoordinationCenterParticipatingcenterNo
7、n-participatingcentern=13GAandBWdistributionofNRFGA35.0±4.0wkBW2267±804gPreterm62.5%100NCPAPandCMV20604080%HebeiGDPandpopulation(2007)VariablesHebeiChinaPopulation69M1,300MGDP(CNY)19,36318,665Disposableincomeofurbanresidents(CNY)11,69113,786Birthrate(‰)13.312.1Hebeivs.nation-wid
8、estudyVariablesHebeiNation-wideYear2007-2008200
