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1、广州医科大学硕士学位论文ResultsNopatientswerelostinthefollow-up,thefollow-uptimerangedfrom38to64monthsandaveraged50months.JOAscorewere11.5±3.2preoperativelyand21.3±2.7atthefirstweekpostoperatively,26.3±1.7atlastfollow-up,respectively.Therewasstatisticalsignifica
2、ncebetweenpreoperativeandallthepostoperativeJOAscores(P<0.05),andnosignificantdifferencebetweenthelastfollow-upand12monthspostoperatively(P>0.05).Significantimprovementaftersurgeryhadbeenshownin34patientswithJOAimprovementraterangingfrom65%to96%andav
3、eraged85%.TheeffectivenessaccordingtoJOAscoringatlastfollow-up,wereexcellentin30cases(88.2%),goodin4(11.8%),therateofexcellentandgoodwas100%.Theaveragedischeightwere9.7±1.4mmpreoperatively,and11.5±1.4mmat1week,9.9±1.3mmat6monthspostoperativelyand9.5±
4、1.4mmatfinalfollow-up,respectively.Therewasstatisticalsignificancebetweenpreoperativedischeightanddischeightat3monthspostoperatively(P<0.05),andnosignificantdifferencebetweenpreoperativedischeightanddischeightat6monthspostoperatively(P>0.05).Atlastfo
5、llow-up,finsbrokenwasfoundin6case,andsubsidencemorethan3mmin5casesandlooseanddisplacementmorethan3mmoutoftheposterioredgeofvertebraloccurredin2cases,discheightlossmorethan1.5mmwasfoundin3cases,butallofthesecasesweresymptomfree.Adjacentdegenerationwas
6、foundin2cases,oneofwhomneededdecompressionandpediclescrewfixation;theotherwastreatedwithconservativetreatment.Solidunionoccurredin16cases(42.1%)andprobableunionin22cases(57.9%),non-unionwasfoundinnoneofallthecasesbySuk’scriteriaatfinalfollow-up.Concl
7、usion1.Thelong-termefficacywassatisfiedintermsofpainrelievewiththetreatmentforlumbardegenerativediseasewithfusionusingsingleB-TwinESSthroughmicroendoscopicapproach,whichmeettheneedsofminimallyinvasivetreatment,buttheoccurrenceoffinsbroken,looseningan
8、dsubsidencewererelativelyhigh.Thedesignofspacerandthesolidfusionratewereneededtobeimproved.2.ThecombinationofdecompressionmicroendoscopicallyandfixationwithB-Twinexpandablespacermayserveasanidealminimallyinvasiveprocedurefor4万方数据英文摘要decompressionandf